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Microarray manufacturing is an area that is plagued with numerous technical challenges due, in part, to the complexity of the systems involved and to the variety of proteins and potential assays used.
http://www.labmgr.com/articles.asp?pid=52

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This article reviews current trends in manufacturing processes that IVD companies are implementing to achieve higher performance reproducibility from test to test, as measured by coefficient variability (CV), and better efficiency for high volume manufacturing. This article also focuses on processes such as application of various chemistries onto supporting materials, drying of such porous materials, and laminating and cutting all processed materials into finished test strips that are adequate for LFIAs.
In-line processing trends for lateral-flow immonuassay manufacturing