Application

Lyobead

The Lyobead manufacturing process begins with bead creation – the dispensing and freezing of liquid, reagent, or drug using technologies that deliver singulated beads of the desired size and shape. BioDot’s platform design expertise applied to the Lyobead formation challenge resulted in the established new Sphera™ discrete dispensing technology.

Sphera™ Technology

Superior Performance
Better Yield
Higher Throughput
Expanded Dynamic Range

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Sphera™ Lyobead Dispensing Platform

BioDot's Sphera Technology offers turn-key solutions for LyoBead production that include a bead dispenser, sealable tray, and freeze dryer. The combination provides all the necessary parts to quickly implement using Lyobeads

2μL- 30μL Automated Spherical Lyobead formation
7,000-60,000 beads per hour
In-Process Bead Volume Tuning

Sphera Lyobead

Sphera™

1-4

Bulk Dispense / Beads and Spheres

Freezing beads in liquid nitrogen bath

Dispense area in bath: X ~315mm (dependent on number of channels) / Y=250mm. 240 partition holes, 13mm hole D / 15mm pitch / Bead dispensing 10,000 – 40,000

BioDot Studio

BioJet PN

Tip selection and geometry / Can use own partition / Reagent temperature control

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